ORGANIC SYNTHESIS AND GREEN CHEMISTRY

I. RESEARCH AREAS 

- Conversion of biomass and natural products: extracting a variety of essential oils from oil-bearing plants, synthesizing camphor from pine essential oils, some compounds from citronellal essential oils, or carvenon from citrus essential oils, preparing biodiesel from waste fish fat, corn-cob, bagasse, isolating seed gum from natural plants as coagulant to treat waste water, purifying and modifying clay materials into Montmorillonite K-10 as acidic solid supports,...

- Syntheses of Metal Organic Frame: Zirconium (Zr-MOFs) from linker containing carboxylic acid, ethynyl group,....

- Syntheses of pharmaceutical compounds: antibacteria (cephalexin, cefixime, fluoroquinoline, cefaclor...), anti-fungi (thiosulfonate S-esters, sulfonamide...), vitamins (vitamin PP, vitamin B₁,...), anticancer (vinblastin, sulforaphan,...),...

- Syntheses of agro-chemical compounds: sex pheromones, insecticide, ...

- Syntheses of cosmetic chemicals: a constituent of perfume (amylcinnanaldehid...), preservatives (paraben group), emolients (fatty acid esters,...),...

- Syntheses of compounds for food chemistry: antifungy (ferullic acid...),...

- Application of green energy: microwave or ultrasound irradiation in most of synthetic pathways or essential oil extraction. 

II. GROUP MEMBERS

1. LUU Thi Xuan Thi, Ph.D. – This email address is being protected from spambots. You need JavaScript enabled to view it. (CV)

2. DOAN Ngoc Nhuan, Ph.D. – This email address is being protected from spambots. You need JavaScript enabled to view it. (CV)

3. NGUYEN Thi Thao Tran, Ph.D. – This email address is being protected from spambots. You need JavaScript enabled to view it. (CV)

4. TRAN Hoang Phuong, Ph.D. – This email address is being protected from spambots. You need JavaScript enabled to view it. (CV)

5. NGUYEN Tan Tai, Ph.D. – This email address is being protected from spambots. You need JavaScript enabled to view it. (CV)

6. MSc. TAN Hoang – This email address is being protected from spambots. You need JavaScript enabled to view it. 

7. MSc. LE Hoang Giau – This email address is being protected from spambots. You need JavaScript enabled to view it.

III. TYPICAL PUBLICATIONS

1. T. X. T. Luu, T. T. T. Nguyen, T. N. Le, J. S. Larsen,  F. Duus, Fast and efficient green synthesis of thiosulfonate S-esters by microwave supported permanganate oxidation of symmetrical disulfides. Journal of Sulfur Chemistry, 2015, 36 (3), 340-350.

2. T. X. T. Luu, H. T. Le, T. N. Le, F. Duus, Microwave- and ultrasound- accelerated green permanganate oxidation of thioethers. Organic Chemistry: Current Research, 2015, 4(1), 129-134.

3. P. H. Tran, V. H. Huynh, P. E. Hansen, D. K. N. Chau, T. N. Le, An efficient and green synthesis of 1-indanone and 1-tetralone via intramolecular Friedel-Crafts acylation reaction, Asian Journal of Organic Chemistry, 2015, 4 (5), 482-486.

4. P. H. Tran, H. M. Hoang, P. E. Hansen, D. K. N. Chau, T. N. Le, Indium triflate in 1-isobutyl-3-methylimidazolium dihydrogenphosphate: an efficient and green catalytic system for Friedel–Crafts acylation, Tetrahedron Letters, 2015, 56(17), 2187-2192

5. P. H. Tran, P. E. Hansen, H. T. Nguyen, T. N. Le, Erbium trifluoromethanesulfonate-catalyzed Friedel–Crafts acylation using aromatic carboxylic acids as acylating agents under monomode-microwave irradiation, Tetrahedron Letters, 2015, 56 (4), 612-618

6. T. T. T. Nguyen, D. K. N. Chau, F. Duus, T. N. Le, Green synthesis of carvenone by montmorillonite-catalyzed isomerization of 1,2-limonene oxide, International Journal of Organic Chemistry, 2013, 3(13), 206- 209.

7. T. T. T. Nguyen, T. T. Diep, V. Hoang, T. H. M. Vo, F. Duus, T. N. Le, Investigation of curry leaf essential oils of Murraya koenigii Spreng growing in the South of Vietnam, Journal of Essential Oil Bearing Plants, 2012, 15 (6), 1021-1029.

8. L. H. T. Doan, T. N. Le, Switch of reaction pathway induced by solid support and ultrasound, Synthetic Communications, 2012, 42, 337-340.

9. K. Snégaroff, T. T. Nguyen, N. Marquise, Y. S. Halauko, P. J. Harford, T. Roisnel, V. E. Matulis, O. A. Ivashkevich, F. Chevallier, A. E. H. Wheatley, P. C. Gros, F. Mongin, Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships, Chemistry - A European Journal, 2011, 17, 13284-13297.

10. T. T. Nguyen, N. Marquise, F. Chevallier, F. Mongin, Deprotonative metalation of aromatic compounds by using an amino-based lithium cuprate, Chemistry - A European Journal, 2011, 17, 10405-10416.

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